Nearly Complete Response of Brain Metastases from HER2 Overexpressing Breast Cancer with Lapatinib and Capecitabine after Whole Brain Irradiation

نویسندگان

  • Esin Oktay
  • Özlem Yersal
  • Nezih Meydan
  • Mehmet Sağıroğlu
  • Ömer Uyanık
  • Sabri Barutca
چکیده

Trastuzumab treatment does not prevent intracranial seeding and is largely ineffective for established central nervous system metastasis in HER2 overexpressing breast cancer patients. Combination therapy of lapatinib and capecitabine may be an effective treatment option for brain metastasis of HER2-positive breast cancer. We report a patient with breast cancer overexpressing HER-2 where brain metastases were successfully treated with radiation and a combination of lapatinib and capecitabine.

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Brain Metastases of Her2-Positive Breast Cancer: A Case of 34 Months’ Remission with Lapatinib plus Capecitabine

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عنوان ژورنال:

دوره 2013  شماره 

صفحات  -

تاریخ انتشار 2013